Mitochondrial functional resilience after TFAM ablation in the adult heart
نویسندگان
چکیده
منابع مشابه
Human mitochondrial DNA is packaged with TFAM.
Mitochondrial transcription factor A (TFAM), a member of the high mobility group proteins, is essential for maintenance of mitochondrial DNA (mtDNA). Most TFAM and mtDNA (both of which are normally soluble) was recovered from the particulate fraction of human placental mitochondria when extracted with the non-ionic detergent Nonidet P-40. mtDNA and TFAM were co-immunoprecipitated by anti-TFAM a...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Cell Physiology
سال: 2021
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00508.2020